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Diet and Lifestyle

Crohn’s disease and milk

Crohn’s is a condition that affects one in 800 people in the UK and causes chronic intestinal inflammation, leading to pain, bleeding and diarrhoea.

It is thought that the Mycobacteria make their way into the body’s system via cows’ milk and other dairy products.  In cattle it can cause an illness called Johne’s disease – a wasting, diarrhoeal condition.

Until now, however, it has been unclear how this bacterium could trigger intestinal inflammation in humans.

Professors at University’s School of Clinical Sciences, explains: “Mycobacterium paratuberculosis has been found within Crohn’s disease tissue but there has been much controversy concerning its role in the disease.  We have now shown that these Mycobacteria release a complex molecule containing a sugar, called mannose.  This molecule prevents a type of white blood cells, called macrophages, from killing internalised E.Coli. 

Scientists have previously shown that people suffering from  with Crohn’s disease have increased numbers of a ‘sticky’ type of E.coli and weakened ability to fight off intestinal bacteria.

The suppressive effect of the Mycobacterial molecule on this type of white blood cell suggests it is a likely mechanism for weakening the body’s defence against the bacteria.

Scientists also found that this bacterium is a likely trigger for a circulating antibody protein (ASCA) that is found in about two thirds of patients with Crohn’s disease, suggesting that these people may have been infected by the Mycobacterium.

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Diet and Lifestyle

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Diet and Lifestyle

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Vitamin C, also known as ascorbic acid, is necessary for the growth, development and repair of all body tissues. It’s involved in many body functions, including formation of collagen, absorption of iron, the proper functioning of the immune system, wound healing, and the maintenance of cartilage, bones, and teeth.

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Diet and Lifestyle

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