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  • Crohn’s disease is characterised by long-lasting inflammation of the gastrointestinal tract.
  • While it can manifest in any part, the area most likely to be affected is the final section of the small intestine or the terminal ileum.
  • The typical pattern is that some parts continue to be healthy, while others become diseased and ulcerated.  
  • It is a chronic illness, so while some associated symptoms can be alleviated, it can never be fully cured.
  • It may be diagnosed at any age, although most diagnoses are made between the ages 15 and 35 years.

Symptoms of Crohn’s Disease

The symptoms commonly associated with Crohn’s disease are chronic diarrhoea, nausea, constipation, cramps, abdominal pain, gas, ulcers, fatigue, fistulas, low grade fevers and appetite loss. Fluctuating between periods of remission followed by flare-ups can lead to thickening of the intestinal walls caused by inflammation. This, in turn, can result in scarring of the tissue and intestinal blockages.

Symptoms can vary, ranging from mild to severe. They can also fluctuate over time, and affect individuals in different ways, depending on the section of the gastrointestinal tract that is most inflamed. Being able to distinguish between normal health and illness is the best way to establish if a flare-up is occurring or not. 

People with Crohn’s disease are more at risk of developing nutritional deficiencies. This can be as a result of avoiding certain foods, so as to prevent abdominal pain or other symptoms from occurring. It can also arise due to dietary nutrients not being absorbed properly because of damage to the intestinal walls. Consequently, this can lead to high prevalence rates of vitamin B insufficiency among people living with this condition. 

A psychological assessment is often carried out before a definitive diagnosis of Crohn’s disease is reached. For example, fatigue, is a commonly occurring symptom, which can significantly affect an individual’s quality of life, ability to work and other aspects of daily living. It can also generate pain, as well as lead to mental health problems, such as anxiety and depression.

While some people may be experiencing the symptoms associated with the condition for a period of time, nevertheless, they may still be seeking answers to a number of questions following a recent diagnosis. It is advisable that people living with this illness learn as much about it as possible, as those who are well-informed and knowledgeable are more likely to become active participants in decision-making regarding interventions and treatment.

Click here to see more on the symptoms of Crohn’s Disease…

Cause of Crohn’s Disease

While the root cause of this condition has not been clearly established, inflammation is one of the classic symptoms of autoimmune disease. The latter triggers a response whereby the body mistakenly attacks healthy intestinal cells or good bacteria, believing them to be a threat. When such reactions occur, on an ongoing basis, then chronic inflammation is an inevitable outcome. Occasionally, autoimmune responses can produce other negative effects in other parts of the body.

Who is more likely to Develop Crohn’s Disease?

While it is possible to develop Crohn’s disease at any age, people in the 15–35 years age group are more likely to receive a diagnosis of this condition.

No gender differences in prevalence rates have been detected, in that it is equally common in both men and women. However, variations do occur in terms of racial background, with white people being more likely to be affected than other races.

In addition, people of Jewish origin are more susceptible to irritable bowel disease, and they have been found to be between three and six times more likely to suffer from this condition. 

There are genetic risk factors associated with Crohn’s disease. Essentially, those with a specific gene mutation have been found to be more prone to developing the illness. Studies have also showed that the same gene mutation is linked with other inflammatory conditions, for example, rheumatoid arthritis. Therefore, people with a Crohn’s disease diagnosis may be of greater risk of also developing arthritis.

Normal Functioning of the Gastrointestinal System 

(often known as from cheek to cheek!)

When seeking to learn more about Crohn’s disease, as with any other topic, an important first step is to begin with some basic knowledge and then progress to acquire more in-depth detail. It is also beneficial to gain a better understanding of what a healthy bowel constitutes, prior to finding out about bowel disease.

The gastrointestinal system normally functions as follows. The gastrointestinal tract is a hollow muscular tube which begins at the oral cavity, where food first enters the system through the mouth. Next it progresses through the pharynx, which is located in the throat behind the nasal cavity, and then on into the oesophagus, also known as the gullet. There, digestive juices break down the food, before it moves along to the small and large intestines and then through the rectum and anus, before it leaves the body through the anus as faeces (as illustrated in the diagram above).

A number of different accessory organs secrete enzymes which help the track by breaking down proteins and fats. This assists to push the food forward along the gastrointestinal tract through peristaltic movement of the muscular wall. Peristalsis describes involuntary contractions which create wave-like movements, which propel the food along until it is eventually eliminated as waste.

Therefore, the primary function a healthy bowel performs is to digest food, retain and absorb all usable minerals and nutrients (including amino acids, fatty acids, vitamins and so on) and later expel solid material as faeces from the body.

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About Crohn's Disease

Still Tired liveing with crohns

When my Crohn’s disease is active, my fatigue can be debilitating. Sometimes I’m forced to stop answering phone calls because I literally don’t have the energy to construct sentences. I don’t allow myself to drive because it doesn’t feel safe. I’m basically unable to do anything except the bare minimum, and when I come out on the other side I feel like I’ve been in the deepest fog.

How can I be so tired?

After experiencing fatigue like this on and off for quite a while, I began to wonder how I could possibly be SO tired. I was ‘sleeping’ ten to twelve hours a night and taking a nap during the day. What more could my body possibly want? I wasn’t working. I wasn’t moving much. In fact, I wasn’t using any more strength than necessary, and yet, it still felt like too much.

Anyone with IBD knows that when you’re sick, it often feels like more than just stool emptying from your bowels. It feels like life is emptying out too.

Fatigue and mental health

I found the fatigue contributed to my anxiety and depression, affecting my mental health too. It seemed like I was trapped in this awful cycle and all I could do is come up for air between episodes.

During that time, I took prescription sleep medication, I worked with a sleep doctor, and underwent multiple normal sleep studies. I even followed suggestions on reducing screen time, creating sleep hygiene and more, but no matter what, I felt exhausted all of the time.

Sleep versus rest

This was when I learned the difference between being asleep, and getting rest. Being in bed, tossing and turning, waking up during the night – they all impact our ability to achieve deep sleep cycles characterized by faster breathing, a faster pulse, and rapid eye movements, or REM. There were times that my body may have been unconscious, but it most certainly wasn’t at rest.

It became clear to me that I had to learn how to dedicate time to conscious rest when I was awake. To be honest, this felt awkward and like something I was embarrassed about. Have you ever sat down to do something like this?

Changes I made

There were three changes I made that over time have significantly impacted my levels of fatigue, and I’d really like to offer them as suggestions to anyone who is struggling.

  1. Scrolling through social media, even while laying in bed, doesn’t count as resting. When you brain is actively thinking about things you want, need, or are missing out on, it impacts your body’s ability to rest. Schedule in some breaks to put your phone down.
  2. Guided imagery and meditation are real things that relax your mind AND your body. I rely on the Calm app, but there are others out there as well which offer you these services right from your phone. Quieting your brain quiets your body in a real, lasting way.
  3. Aromatherapy – certain scents are tied to physical relaxation. Whether you purchase a linen spray, light a candle, burn incense or diffuse essential oils, or take a bath with bubbles or salts or bombs, aromatherapy draws upon the healing powers of the leaves, flowers, stems, bark, roots or petals of plants to stimulate the natural healing action of both your body and your mind.
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About Crohn's Disease

Tips on Asking for Support During Crohn’s or UC Flares

If you’re living with inflammatory bowel disease, you know that your life, health, abilities, and capabilities can change dramatically in a short period of time. From my experience, no matter how much I plan for the next flare, there are always things I wish I had done, I need but don’t have, or I would really benefit from help.

Asking for help during a Crohn’s or UC flare

I’ve thought a lot about this and about how it feels hard to ask for help. I don’t usually know what to ask for directly so I often keep quiet, and I never know who exactly I should reach out to in the event that I need (or want!) physical things or tangible assistance.

I wanted to share with you some thoughts I’ve put together after a lot of trial and error. To be honest, it’s SO MUCH better for my mental health and my stress levels as my symptoms increase to know that I know how to best ask for support and that I’m not alone in my trials, especially when this disease can feel so isolating.

Things that are helpful when dealing with a flare

In no particular order, here are some things that have worked for me:

  1. Keep a list in your phone of a few people who are local that you trust, and that might be able to do you a favor when you don’t feel well. Depending on your needs, this might mean stopping at the store, dropping off a cooked meal, picking up a prescription, taking you to a doctors appointment, sitting with you in the ER or visiting you at home or in the hospital.
  2. Then, add to the bottom of that list, a few people who might not necessarily be nearby, but who understand your heart. People you can call or facetime or text when you want to cry or vent or be distracted. One important note here: don’t leave out your other friends with IBD! I’ve often avoided telling them that I was doing poorly because I knew they had struggles of their own, and in retrospect, they wished they’d been able to be there for me. They understood my plight directly and agreed they’d tell me if whatever I was telling them or asking them in terms of support felt like too much at any given time.
  3. Think about your necessities during a flare: what foods or meal replacements you can tolerate, what clothes and basic household items that you both need and that would make you more comfortable, and anything that might cheer you up.
  4. If you have a roommate, live with family, have a spouse, children or pets, think about if they can help and/or have needs of their own while you are down and out.
  5. In the event that a friend or family member reaches out and asks what they can do for you, or what they can bring you or send to you, I’ve found politely declining over and over is a loss for both myself and the other person. They genuinely want to help, and I honestly could use it. I have found it to be easiest to have direct and tangible items I can ask for – such as groceries, prepared meals (or meal delivery), conversation to take my mind off of things or company when I don’t have the energy to talk.

Living with inflammatory bowel disease is hard enough, there’s absolutely no reason to decline help or support simply because you don’t know how to ask, or don’t want to inconvenience someone who has already offered.

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About Crohn's Disease

Inflammatory Bowel Disease

What is Inflammatory Bowel Disease (IBD)
Inflammatory Bowel Disease is a group of chronic lifelong conditions affecting the digestive tract. It includes both Ulcerative Colitis (UC) and Crohn’s Disease (CD) which are similar but affect different parts of the intestine. UC affects the inner lining of the large intestine while CD can affect any part of the digestive tract from the mouth to the anus. You can read further information on IBD in this patient information leaflet

Clinical features of Inflammatory Bowel Disease
The main features of IBD are bloody diarrhoea associated with frequency, urgency and abdominal cramps.  In severe attacks patients may suffer weight loss and anorexia.

In addition patients may have symptoms from outside the digestive tract including:

•         Arthritis (large joints)
•         ankylosing spondylitis
•         erythema nodosum
•         pyoderma gangrenosum
•         iritis and episcleritis (inflammation of the eyeball)
•         primary sclerosing cholangitis (75% pts have IBD, Geonzon –Gonzales 2006)

How common is IBD?

•         15,000 people in Ireland have IBD
•         Incidence in Ireland – 6,000 UC
                                        – 3,000 CD

What causes IBD?
The cause of IBD is unknown but is thought to include:   Genetic susceptibility
A familial tendency 
Environmental factors -smokingstress

non-steroidal anti-inflammatory drugs  

history of appendectomy

history of infection with mycobacteria  

activation of the immune system

possibly diet but not proven

•         Infective agents
•         Seasonal changes
•         Stress – implicated in aetiology of disease  (Mawdsley & Rampton 2005)

Treatment of IBD
Treatment for IBD is often simple and includes both local and oral medications, often the condition can be managed in the community by the patient’s General Practitioner after consultation with a Specialist. Regular review by a specialist is recommended for complex therapies and disease. Surgery may be required in difficult cases.

Mary Kennedy is the IBD Clinical Nurse Specialist at TUH. The IBD nurse is often your first point of contact if you require any advice regarding your disease. She provides a rapid point of access for IBD patients, in particular she can provide support, advice and information on your inflammatory bowel condition. Also, she will play an active role in disease and drug education and management. Treatments such as Infliximab (Remicade) and Adalimumab (Humira) are administered by the IBD Nurse.

An advice line is run by the IBD Nurse and the contact number is 01 414 3855.

TUH Gut Therapy Programme for IBS
The chronic diarrhoea pathway aims to provide patients with diarrhoea symptoms of Irritable Bowel Syndrome (IBS) with fast access to the most appropriate investigations and management of their condition. Patients aged over 45 with chronic diarrhoea of more than one month duration will be automatically be triaged for a colonoscopy. If this and blood tests are normal they subsequently attend the dietitian led gut therapy clinic.

Patients aged under 45 with chronic diarrhoea of more than one month duration with red flag symptoms such as bleeding, weight loss, anaemia and family history of bowel cancer or IBD will also be automatically be triaged for a colonoscopy. If this and blood tests are normal they subsequently attend the dietitian led gut therapy clinic. 

Patients under 45 who do not have red flag features will have blood and stool tests done. If these are normal they attend the dietitian led gut therapy clinic, if an abnormality is detected they have a colonoscopy and are managed as appropriate after that.

Its most notable attribute is its effect on wound management and healing. Manuka honey also has antibacterial, antiviral and anti-inflammatory properties that may help treat numerous ailments, including irritable bowel syndrome, gastric ulcers, periodontal disease and upper respiratory infections.

Honey is well known for its anti-inflammatory and antioxidant capacities, which may be useful for the prevention of chronic inflammatory process like atherosclerosis, diabetes mellitus and cardiovascular diseases. The antibacterial, anti- inflammatory and antioxidant properties of honey

What is the fastest way to get rid of inflammation in the body?Follow these six tips for reducing inflammation in your body:

  1. Load up on anti-inflammatory foods. …
  2. Cut back or eliminate inflammatory foods. …
  3. Control blood sugar. …
  4. Make time to exercise. …
  5. Lose weight. …
  6. Manage stress.

Does b12 reduce inflammation?Vitamin B6, folate (B9), and B12 can lower your levels of homocysteine, an amino acid that’s linked to a greater risk for heart disease and rheumatoid arthritis. But we can’t say for sure that lowering homocysteine will also lower your risk for disease. The same is true for C-reactive protein, a sign of inflammation.

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click here to buy vitamin 12
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